Author

K. Hirazawa

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1

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Approach:biophysical modeling· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

T. Shimomura· 1 shared Y. Kubo· 1 shared

Activity by Year

2022-2022 · peak 1/yr

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2 top collaborators · 1 mutual co-author link

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1 shared paperBiophysics

T. Shimomura

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1 paper

Recent·Most cited

Conformational rearrangements in 2nd voltage sensor domain switch PIP2- and voltage-gating modes in two-pore channels

T. Shimomura, K. Hirazawa, Y. Kubo

This study shows that conformational changes in the voltage-sensor domain of TPCs determine whether they are PIP2- or voltage-gated, and that these modes can be switched by small molecules.

bioRxiv · Jun 14, 2022 · PreprintBiophysics