Systematic genetic mapping of necroptosis identifies SLC39A7 as modulator of death receptor trafficking
A. Fauster, M. Rebsamen, K. L. Willmann, A. Cesar-Razquin, E. Girardi, J. W. Bigenzahn, F. Schischlik, S. Scorzoni, M. Bruckner, J. Konecka, K. Hörmann, L. X. Heinz, K. Boztug, G. Superti-Furga
The paper uses genetic screens to identify SLC39A7 as a modulator of necroptosis by affecting TNF receptor trafficking and ER homeostasis.
bioRxiv · Mar 29, 2018Cell Biology