PathologybioRxivPreprint
SilencioMA: A single compound that targets both MAPT and APP as a potential disease modifying therapeutic for Alzheimer's Disease
P. Sgourdou, N. Vrettos, K. Hoxha…·Zissimos Mourelatos
This paper develops SilencioMA, a compound targeting both MAPT and APP mRNAs, showing reduced Aβ and tau pathology in a mouse model of Alzheimer's Disease.
DOI 10.64898/2026.11.09.765491