Proinflammatory responses in SARS-CoV-2 infected and soluble spike glycoprotein S1 subunit activated human macrophages
K. Chiok, K. Hutchison, L. G. Miller, S. Bose, T. A. Miura
This study shows that soluble SARS-CoV-2 Spike S1 subunit activates human macrophages to produce pro-inflammatory mediators, independent of viral replication.
bioRxiv · Jun 14, 2021Immunology