HDAC6 inhibition partially alleviates mitochondrial trafficking defects and restores motor function in human motor neuron and zebrafish models of Charcot-Marie-Tooth Disease Type 2A
L. Butler, K. I. Adamson, S. L. Johnson, L. Jestice, C. J. Price, D. Stavish, N. Pooranachandran, A. Tsakiridis, A. Grierson, I. Barbaric
This study shows HDAC6 inhibition improves mitochondrial trafficking and motor function in CMT2A models using human motor neurons and zebrafish.
bioRxiv · Jul 5, 2022 · PreprintCell Biology