Matrix elasticity gradients guide neuronal polarity by controlling microtubule network mobility
M. Burute, K. I. Jansen, M. Mihajlovic, T. Vermonden, L. Kapitein
This study shows that extracellular elasticity gradients guide neuronal polarity by controlling microtubule network mobility and Rho-GTPase activation, leading to polarized transport and axon specification.
bioRxiv · Jul 22, 2021 · PreprintCell Biology