Overlooked Candida glabrata petites are echinocandin tolerant, induce host inflammatory responses, and display poor in vivo fitness
A. Amir Arastehfar, F. Daneshnia, H. Hovhannisyan, D. Fuentes, N. Cabrera, C. Quinteros, M. Ilkit, N. Ünal, S. Hilmioglu-Polat, K. Jabeen, S. Zaka, J. V. Desai, C. Lass-Flörl, E. Shor, T. Gabaldon, D. S. Perlin
This study investigates petite C. glabrata strains, showing they are echinocandin tolerant, induce inflammation, and have poor in vivo fitness, with low global prevalence.
bioRxiv · Jun 15, 2023 · PreprintMicrobiology