A selectivity filter in the EMC limits protein mislocalization to the ER
T. Pleiner, M. Hazu, G. P. Tomaleri, V. N. Nguyen, K. Januszyk, R. M. Voorhees
The paper shows the EMC uses a selectivity filter to prevent mitochondrial tail-anchored proteins from mislocalizing to the ER.
bioRxiv · Nov 29, 2022Cell Biology