Outer membrane vesicles derived from Salmonella Typhimurium can deliver Shigella flexneri 2a O-polysaccharide antigen to prevent lethal pulmonary infection in mice
Q. Liu, H. Tian, B. Li, Y. Chen, K. Jie, T. Xu, Z. Song, X. Huang
This study develops an OMV-based vaccine using Salmonella Typhimurium to deliver Shigella flexneri 2a O-polysaccharide antigen, showing protection against lethal pulmonary infection in mice.
bioRxiv · Feb 1, 2021Microbiology