Z. Song

Whole-genome resequencing revealed the Origin and Domestication of Chinese Domestic Rabbits

This study uses whole-genome resequencing to trace the origin and domestication of Chinese domestic rabbits, identifying genetic adaptations and multiple potential origins.

Short-term memory, attentional control and brain size in primates

This study examines the relationship between brain size and short-term memory in primates, finding that overall brain size better predicts performance than specific brain regions or encephalization quotient.

Early evolution of the ecdysozoan body plan

The paper describes a new Cambrian ecdysozoan species, Beretella spinosa, and suggests that ancestral ecdysozoans may have been non-vermiform.

Phenotypic and transcriptional features of the Araliaceae species under distinct light environments

This study compares phenotypic and transcriptomic features of sun- and shade-grown Araliaceae species under different light conditions, revealing differences in photosynthesis efficiency and gene regulation.

Parallel Molecular Data Storage by Printing Epigenetic Bits on DNA

This paper introduces a DNA-based data storage method using epigenetic modifications, achieving scalable and parallel data writing and retrieval.

An Artificial Intelligence-Assisted Digital Microfluidic System for Multistate Droplet Control

This paper introduces an AI-assisted digital microfluidic system called DropAI for multistate droplet control using semantic segmentation and state machine feedback.

A force-sensitive adhesion GPCR is indispensable in normal equilibrioception

This study identifies LPHN2/ADGRL2 as a force-sensitive adhesion GPCR essential for normal equilibrioception by regulating mechanoelectrical transduction in utricular hair cells.

Force sensing GPR133 is essential for normal balance and modulates vestibular hair cell membrane excitability via Gi signaling and CNGA3 coupling

This study identifies GPR133 as a force-sensing GPCR essential for balance, showing it modulates vestibular hair cell excitability via Gi signaling and CNGA3 coupling.

Estrogen prevents age-dependent beige adipogenesis failure through NAMPT-controlled ER stress pathway

This study shows estrogen prevents age-related failure in beige adipogenesis by controlling ER stress via NAMPT, improving energy expenditure and glucose tolerance in mice.

Aminomutation catalyzed by CO2 self-sufficient cascade amino acid decarboxylases

This paper describes an in vitro biotransformation pathway using two decarboxylases to convert -alanine to {beta}-alanine with 100% carbon atom economy by fixing CO2.

Anti-PD-1-iRGD Peptide Conjugate Boosts Antitumor Efficacy via Engagement Augmentation and Penetration Enhancement of T cells

This paper develops a PD-1-iRGD conjugate that enhances antitumor efficacy by improving T cell engagement and penetration, and expands a unique population of CD8+ T cells in the tumor microenvironment.

Gut microbiota-derived gamma-aminobutyric acid from metformin treatment reduces hepatic ischemia/reperfusion injury through inhibiting ferroptosis

This study shows metformin reduces hepatic ischemia/reperfusion injury by altering gut microbiota to increase GABA, which inhibits ferroptosis.

Hyperphosphorylated Tau Inflicts Intracellular Stress Responses That Are Mitigated by Apomorphine

This study shows hyperphosphorylated tau causes ER stress and inflammation, which are reduced by apomorphine and HO-1 overexpression.

Multiscale Model for Ion Transport in Cellular Media and Applications in Smooth Muscle Cells

This paper develops a multiscale model for ion transport in multicellular tissues and applies it to study smooth muscle cell activation under various stimuli, showing the importance of gap junctions and extracellular potassium.

Vangl2 suppresses NF-κB signaling and ameliorates sepsis by targeting p65 for NDP52-mediated autophagic degradation

This study identifies Vangl2 as a negative regulator of NF-κB signaling in sepsis by promoting autophagic degradation of p65 through NDP52.

Cdkn2a regulates beige fat maintenance through BECN1-mediated autophagy

This study shows that Cdkn2a regulates beige fat maintenance via BECN1-mediated autophagy, with implications for obesity and diabetes treatment.

Divorce rate in birds increases with male promiscuity and migration distance

The paper analyzes divorce rates in birds using phylogenetic methods and finds male promiscuity and migration distance correlate with higher divorce rates.

Swim bladder resonance enhances hearing in crucian carp (Carassius auratus)

The paper demonstrates that swim bladder resonance enhances hearing in crucian carp through auditory evoked potentials, Micro-CT, and numerical simulations.

Collective invasion of the basement membrane in breast cancer driven by forces from cell volume expansion and local contractility

This study shows breast cancer cells invade the basement membrane using both proteases and mechanical forces from cell volume expansion and local contractility.

Sex differences in the nasal microbiome of healthy young adults

This study analyzes the nasal microbiome of healthy young adults, revealing sex-specific differences in composition and ecological stability between males and females.

Ultra-high-throughput microbial single-cell whole genome sequencing for genome-resolved metagenomics

This paper develops an ultra-high-throughput method for microbial single-cell whole genome sequencing to study microbial dark matter and improve metagenomic analysis.

Cavitation Induced Fracture of Intact Brain Tissue

This study measures fracture energy in intact brain tissue using needle-induced cavitation and hydraulic fracture models, finding values between 1.5 to 8.9 J/m2 depending on location and model.

Right atrial mechanism contributes to atrial fibrillation in a canine model of pulmonary arterial hypertension

Phenotypic and transcriptomic responses of the sun- and shade-loving plants to sunlight and dim-light conditions

This study compares phenotypic and transcriptomic responses of sun- and shade-loving plants to sunlight and dim-light conditions, finding that shade-loving ginseng shows lower phenotypic plasticity but higher photosynthetic efficiency under dim light.

DNA methylation in transposable elements disrupts the connection between three-dimensional chromatin organization and gene expression upon rice genome duplication.

This study investigates how DNA methylation in transposable elements disrupts the link between 3D chromatin organization and gene expression in rice after genome duplication.

The SPEECHLESS-induced stomatal increase is required for the salt tolerance of oil palm

This study investigates how salt stress affects oil palm by analyzing gene expression and stomatal development, finding that EgSPCH promotes stomatal increase which aids in salt tolerance.

Broad ultra-potent neutralization of SARS-CoV-2 variants by monoclonal antibodies specific to the tip of RBD

This paper identifies a monoclonal antibody, 2G1, that neutralizes all SARS-CoV-2 variants with high potency and describes its mechanism of action and therapeutic efficacy in animal models.

Crotamiton derivative JM03 extends lifespan and improves oxidative and hypertonic stress resistance in Caenorhabditis elegans via inhibiting OSM-9

This study identifies JM03, a crotamiton derivative, as a small molecule that extends C. elegans lifespan and improves stress resistance by inhibiting OSM-9 and activating SKN-1 signaling.

Black Dots: Microcontact-Printed, Reference-Free Traction Force Microscopy

This paper introduces a traction force microscopy technique called 'black dots' to measure cellular forces without constraining cell shape, finding that higher force correlates with increased spread area, circularity, and F-actin uniformity in platelets.

Selenium in wheat from farming to food

This paper reviews selenium content in wheat farming soil, grain, and derived foods globally, showing how agronomic practices can enhance selenium levels in wheat and its products.