Author

K. L. Diehl

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:biophysical modeling· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Organism:E. coli· 1 Approach:experimental assay· 1

Frequent Co-Authors

A. Bajic· 1 shared A. H. Ablicki· 1 shared A. Q. Rashoff· 1 shared A. R. Colligan· 1 shared B. A. Garcia· 1 shared D. M. Eckert· 1 shared G. A. Desjardins· 1 shared J. J. Smith· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperCancer Biology

A. Bajic

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Author profile →

2 papers

Recent·Most cited

A genetically-encoded fluorescent biosensor for visualization of acetyl-CoA in live cells

J. J. Smith, T. R. Valentino, A. H. Ablicki, R. Banerjee, A. R. Colligan, D. M. Eckert, G. A. Desjardins, K. L. Diehl

This paper develops a genetically-encoded fluorescent biosensor to measure acetyl-CoA in live cells, showing its utility in E. coli and HeLa cells for detecting acetyl-CoA dynamics and compartmentalization.

bioRxiv · Dec 31, 2023Biochemistry

PFA ependymoma-associated protein EZHIP inhibits PRC2 activity through a H3 K27M-like mechanism

S. U. Jain, T. J. Do, P. J. Lund, A. Q. Rashoff, M. Cieslik, K. L. Diehl, A. Bajic, N. Juretic, S. Deshmukh, S. Venneti, T. W. Muir, B. A. Garcia, N. Jabado, P. W. Lewis

This study identifies EZHIP as a PRC2 inhibitor in PFA ependymomas that mimics the H3 K27M oncohistone by disrupting PRC2 activity and H3K27me3 levels.

bioRxiv · Mar 22, 2019Cancer Biology