Author

D. M. Eckert

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:protein folding & dynamics· 2 Assay:proteomics· 2 Approach:biophysical modeling· 1 Organism:C. elegans· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

A. Aggarwal· 1 shared A. E. Siglin· 1 shared A. H. Ablicki· 1 shared A. Laganowsky· 1 shared A. M. Aderounmu· 1 shared A. R. Colligan· 1 shared A. R. Smith· 1 shared A. Tripathi· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 8 mutual co-author links

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1 shared paperBiochemistry

A. Aggarwal

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4 papers

Recent·Most cited

A genetically-encoded fluorescent biosensor for visualization of acetyl-CoA in live cells

J. J. Smith, T. R. Valentino, A. H. Ablicki, R. Banerjee, A. R. Colligan, D. M. Eckert, G. A. Desjardins, K. L. Diehl

This paper develops a genetically-encoded fluorescent biosensor to measure acetyl-CoA in live cells, showing its utility in E. coli and HeLa cells for detecting acetyl-CoA dynamics and compartmentalization.

bioRxiv · Dec 31, 2023Biochemistry

C. elegans Dicer acts with the RIG-I-like helicase DRH-1 and RDE-4 to cleave dsRNA

C. D. Consalvo, A. M. Aderounmu, H. M. Donelick, P. J. Aruscavage, D. M. Eckert, P. S. Shen, B. L. Bass

The paper investigates how C. elegans Dicer collaborates with DRH-1 and RDE-4 to cleave dsRNA, revealing their roles in antiviral defense mechanisms.

bioRxiv · Sep 21, 2023 · PreprintBiochemistry

A Sec14-like Phosphatidylinositol Transfer Protein Paralog Defines a Novel Class of Heme-binding Proteins With An Unusual Heme Coordination Mechanism

D. Khan, D. Lee, G. Gulten, A. Aggarwal, J. Wofford, K. V. Inna, A. Tripathi, J. W. Patrick, D. M. Eckert, A. Laganowsky, J. C. Sacchettini, P. Lindahl, V. Bankaitis

The paper identifies Sfh5 as a novel heme-binding protein with an unusual coordination mechanism, distinct from its Sec14-like PITP family members.

bioRxiv · Mar 19, 2020Biochemistry

Characterization of resistance to a potent D-peptide HIV entry inhibitor

A. R. Smith, M. T. Weinstock, A. E. Siglin, F. G. Whitby, J. N. Francis, C. P. Hill, D. M. Eckert, M. J. Root, M. S. Kay

This study identifies mutations conferring resistance to the D-peptide HIV inhibitor PIE12-trimer and shows they reduce inhibitor affinity but also impair viral fitness.

bioRxiv · Aug 28, 2019Microbiology