Phosphorylation by casein kinase 2 ensures ER-phagy receptor TEX264 binding to ATG8 proteins
H. Chino, A. Yamasaki, K. L. Ode, H. R. Ueda, N. N. Noda, N. Mizushima
The paper shows phosphorylation of TEX264's LIR by casein kinase 2 enhances its binding to ATG8 proteins, crucial for ER-phagy, through hydrogen bonds not achievable with acidic residues.
bioRxiv · Feb 11, 2022 · PreprintCell Biology