Author

K. Langer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Pharmacology & Toxicology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cancer & tumor microenvironment· 2 Organism:human· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Approach:deep learning· 1

Frequent Co-Authors

D. Mulac· 2 shared H. Onafuye· 2 shared J. Cinatl· 2 shared M. Michaelis· 2 shared M. N. Wass· 2 shared S. Pieper· 2 shared B. Seashore-Ludlow· 1 shared E. Akerlund· 1 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersPharmacology & Toxicology

D. Mulac

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4 papers

Recent·Most cited

High-throughput cell spheroid production and assembly analysis by microfluidics and deep learning

M. Trossbach, E. Akerlund, K. Langer, B. Seashore-Ludlow, H. N. Joensson

This paper develops a high-throughput workflow for producing and analyzing miniaturized spheroids using microfluidics and deep learning, optimizing surfactant concentrations and incubation times for three cell lines.

bioRxiv · Oct 2, 2022Bioengineering

Doxorubicin-loaded human serum albumin nanoparticles overcome transporter-mediated drug resistance

H. Onafuye, S. Pieper, D. Mulac, J. Cinatl, M. N. Wass, K. Langer, M. Michaelis

This study shows that doxorubicin-loaded human serum albumin nanoparticles enhance anti-cancer activity in drug-resistant neuroblastoma cells by bypassing ABCB1-mediated efflux.

bioRxiv · May 31, 2019Pharmacology & Toxicology

DRAFT - Robotic automation of production and the recovery of cell spheroids

K. Langer, H. Joensson

This paper automates droplet microfluidics for high-throughput production of human scaffold-free cell spheroids with high viability and throughput.

bioRxiv · Apr 4, 2019Bioengineering

Incorporation of doxorubicin in different polymer nanoparticles and their anti-cancer activity

S. Pieper, H. Onafuye, D. Mulac, J. Cinatl, M. N. Wass, M. Michaelis, K. Langer

This study compares the anti-cancer activity of doxorubicin-loaded nanoparticles made from different polymers and preparation methods, finding significant differences in efficacy based on size, drug load, and release kinetics.

bioRxiv · Aug 29, 2018Pharmacology & Toxicology