Author

K. Lowman

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Microbiology· 1

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Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Dalecki· 1 shared A. Duverger· 1 shared B. Greer· 1 shared D. Moylan· 1 shared E. Carlin· 1 shared F. Wagner· 1 shared M. Perez· 1 shared O. Kutsch· 1 shared

Activity by Year

2020-2020 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperMicrobiology

A. Dalecki

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1 paper

Recent·Most cited

Extensive proteomic and transcriptomic changes quench the TCR/CD3 activation signal of latently HIV-1 infected T cells

E. Carlin, B. Greer, A. Duverger, F. Wagner, D. Moylan, A. Dalecki, S. Samuel, M. Perez, K. Lowman, S. Sabbaj, O. Kutsch

This study identifies proteomic and transcriptomic changes in HIV-1 latently infected T cells that render them TCR/CD3 activation-inert, and shows that targeting specific signaling nodes can restore responsiveness and trigger HIV-1 reactivation.

bioRxiv · Jun 29, 2020Microbiology