Evolutionarily related small viral fusogens hijack distinct but modular actin nucleation pathways to drive cell-cell fusion
K. M. C. Chan, A. L. Arthur, J. Morstein, M. Jin, A. Bhat, D. Schlesinger, S. Son, D. A. Stevens, D. G. Drubin, D. A. Fletcher
This study shows that two FAST proteins use distinct actin nucleation pathways to drive cell-cell fusion, but their cytoplasmic tails are modular and functionally interchangeable.
bioRxiv · Jun 3, 2020Cell Biology