K. M. Dhanabalan

Exploring the potential of water channels for developing MRI reporters and sensors without the need for exogenous contrast agents

This study identifies new water channels as diffusion-weighted MRI reporters and develops sensors for protease activity without exogenous contrast agents.

Sustained release Resolvin D1 liposomes are effective in the treatment of osteoarthritis in obese mice

This study shows that liposomal Resolvin D1 reduces cartilage damage in obese mice with osteoarthritis by increasing anti-inflammatory macrophages.

Rapamycin microparticles induce autophagy, prevent senescence and are effective in treatment of Osteoarthritis

This study develops rapamycin-loaded microparticles that induce autophagy, prevent senescence, and reduce OA symptoms in mice.

Rapamycin-PLGA microspheres induce autophagy and prevent senescence in chondrocytes and exhibit long in vivo residence

This paper develops rapamycin-loaded PLGA microspheres that induce autophagy and prevent chondrocyte senescence, showing sustained drug release and prolonged joint residence in mice.