Tumors Negate the Action of ImpL2 by Elevating Wingless
J. Lee, K. G.- L. Ng, K. M. Dombek, Y. V. Kwon
The paper shows tumors counteract the wasting factor ImpL2 by increasing Wingless, which supports tumor growth and suggests targeting the Wnt/Wg pathway could treat cancers with elevated IGFBPs.
bioRxiv · Sep 16, 2020Cancer Biology