Author

K. M. McFadden

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

S. N. P. Kelada· 2 shared A. Tovar· 1 shared B. Button· 1 shared B. P. Keith· 1 shared B. R. Grubb· 1 shared C. B. Morrison· 1 shared C. Ehre· 1 shared D. B. Hill· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersPharmacology & Toxicology

S. N. P. Kelada

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2 papers

Recent·Most cited

Integrative phenotypic and genomic analyses reveal strain-dependent responses to acute ozone exposure and their associations with airway macrophage transcriptional activity

A. Tovar, W. L. Crouse, G. J. Smith, J. M. Thomas, B. P. Keith, K. M. McFadden, T. P. Moran, T. S. Furey, S. N. P. Kelada

This study identifies strain-dependent responses to ozone exposure in mice and links these to airway macrophage transcriptional activity and chromatin accessibility differences.

bioRxiv · Jan 29, 2021 · PreprintPharmacology & Toxicology

BPIFB1 loss alters airway mucus properties and diminishes mucociliary clearance.

L. J. Donoghue, M. R. Markovetz, C. B. Morrison, K. M. McFadden, T. D. Rogers, B. Button, C. Ehre, D. B. Hill, B. R. Grubb, S. N. P. Kelada

This study shows that BPIFB1 loss in mice impairs mucociliary clearance by altering mucus viscosity without affecting ion transport or ciliary beat frequency.

bioRxiv · Jun 17, 2020Physiology