Author

L. J. Donoghue

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:development & morphogenesis· 2 Approach:experimental assay· 2 Organism:C. elegans· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:metabolomics· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

B. Button· 1 shared B. R. Grubb· 1 shared C. B. Morrison· 1 shared C. Ehre· 1 shared D. B. Hill· 1 shared D. P. Bhatt· 1 shared E. A. Turner· 1 shared I. T. Ryde· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperPhysiology

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2 papers

Recent·Most cited

Early-life mitochondrial DNA damage results in lifelong deficits in energy production mediated by redox signaling in Caenorhabditis elegans

J. P. Rooney, K. A. Hershberger, E. A. Turner, L. J. Donoghue, L. L. Maurer, I. T. Ryde, J. J. Kim, R. Joglekar, J. D. Hibshman, L. L. Smith, D. P. Bhatt, O. R. Ilkayeva, M. D. Hirschey, J. N. Meyer

This study shows that early-life mitochondrial DNA damage in C. elegans causes lifelong energy production deficits through redox signaling mechanisms.

bioRxiv · Nov 25, 2020Cell Biology

BPIFB1 loss alters airway mucus properties and diminishes mucociliary clearance.

L. J. Donoghue, M. R. Markovetz, C. B. Morrison, K. M. McFadden, T. D. Rogers, B. Button, C. Ehre, D. B. Hill, B. R. Grubb, S. N. P. Kelada

This study shows that BPIFB1 loss in mice impairs mucociliary clearance by altering mucus viscosity without affecting ion transport or ciliary beat frequency.

bioRxiv · Jun 17, 2020Physiology