Long-term culture of fetal monocyte precursors in vitro allowing the generation of bona fide alveolar macrophages in vivo
F. Li, K. M. Okreglicka, L. M. Pohlmeier, C. Schneider, M. Kopf
This study demonstrates the in vitro generation of alveolar macrophage-like cells from fetal liver monocytes using GM-CSF, which can engraft in vivo and protect against respiratory infections.
bioRxiv · Jun 4, 2021 · PreprintImmunology