K. Magiera-Mularz

Competition NMR for Detection of Hit/Lead Inhibitors of Protein-Protein Interactions

The paper introduces a sensitive NMR competition assay to detect weak inhibitors of protein-protein interactions, demonstrating its use with Mdm2/X-p53 and PD-1/PD-L1 complexes.

CA-170 a potent small-molecule PD-L1 inhibitor or not?

The paper investigates whether CA-170, a small-molecule PD-L1 inhibitor, binds to hPD-L1 using biophysical assays and finds no direct binding.