The tumor suppressor APC is an attenuator of spindle-pulling forces during C. elegans asymmetric cell division
K. Sugioka, L.-E. Fielmich, K. Mizumoto, B. Bowerman, S. van den Heuvel, A. Kimura, H. Sawa
This study identifies APC as an attenuator of spindle-pulling forces during C. elegans asymmetric cell division, showing it stabilizes microtubule plus-ends and reduces catastrophe frequency.
bioRxiv · Dec 18, 2017Cell Biology