Optogenetic dissection of mitotic spindle positioning in vivo
L.-E. Fielmich, R. Schmidt, D. J. Dickinson, B. Goldstein, A. Akhmanova, S. van den Heuvel
This study uses optogenetics to dissect mitotic spindle positioning in C. elegans embryos, showing that G-GTP signaling is dispensable and LIN-5Mud/NuMA activates dynein-dependent forces.
bioRxiv · May 14, 2018Cell Biology