K. N. Dinh

Inference of chromosome selection parameters and missegregation rate in cancer from DNA-sequencing data

This paper introduces an algorithm to infer chromosome selection parameters and missegregation rates in cancer using DNA-sequencing data, showing it works well with small datasets.

IL-2RαKO mice exhibit maternal microchimerism and reveal nuclear localization of IL-2Rα in lymphoid and non-lymphoid cells

The paper investigates IL-2RαKO mice and finds maternal microchimerism contributes to IL-2R expression in vascular smooth muscle cells, revealing IL-2R's role in regulating cell proliferation in non-lymphoid cells.

Comparison of Tug-of-War Models Assuming Moran versus Branching Process Population Dynamics

The paper compares Tug-of-War models under Moran and branching process dynamics, showing similar statistics and inferring selection coefficients for breast cancer samples, supporting deleterious passenger mutations.

Predicting Minimal Residual Disease in Acute Myeloid Leukemia through Stochastic Modeling of Clonality

This paper develops a stochastic model to predict relapse in AML by analyzing MRD dynamics in a cohort of patients using whole genome sequencing data.