Deficiency of peroxisomal L-bifunctional protein (EHHADH) causes male-specific kidney hypertrophy and proximal tubular injury in mice
P. Ranea-Robles, K. Portman, A. Bender, K. Lee, J. C. He, D. J. Mulholland, C. Argmann, S. M. Houten
This study shows that EHHADH deficiency in mice causes male-specific kidney hypertrophy and proximal tubular injury, linked to androgen effects on peroxisomal metabolism.
bioRxiv · Mar 14, 2021Physiology