Gene Deletion of the PACAP/VIP Receptor, VPAC2R, Alters Glycemic Responses During Metabolic and Psychogenic Stress in Adult Female Mice
E. V. Kozlova, A. E. Bishay, M. E. Denys, B. D. Chinthirla, M. C. Valdez, K. A. Spurgin, J. M. Krum, K. R. Basappa, M. C. Curras-Collazo
This study shows that deleting the VPAC2R gene in female mice increases basal glycemia and impairs insulin response during metabolic stress, while also enhancing hyperglycemia during psychogenic stress.
bioRxiv · Sep 14, 2023Physiology