Author

K. R. Machlus

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell-cell communication· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Assay:metabolomics· 1

Frequent Co-Authors

E. Boilard· 2 shared J. E. Italiano· 2 shared A. J. Murphy· 1 shared A. Morris· 1 shared A. O. Khan· 1 shared A. S. Weyrich· 1 shared D. Freire· 1 shared D. J. Groeneveld· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCell Biology

E. Boilard

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Author profile →

2 papers

Recent·Most cited

Efficient megakaryopoiesis and platelet production require phospholipid remodeling and PUFA uptake through CD36

M. N. Barrachina, G. Pernes, I. C. Becker, I. Allaeys, T. I. Hirsch, D. J. Groeneveld, A. O. Khan, D. Freire, K. Guo, E. Carminita, P. K. Morgan, T. J. Collins, N. Mellett, Z. Wei, I. Almazni, , K. R. Machlus

This study identifies the role of phospholipid remodeling and PUFA uptake via CD36 in megakaryopoiesis and platelet production, showing dietary fatty acids impact platelet counts.

bioRxiv · Feb 12, 2023Cell Biology

Megakaryocyte emperipolesis mediates membrane transfer from intracytoplasmic neutrophils to platelets

P. Cunin, R. Bouslama, K. R. Machlus, M. Martinez-Bonet, P. Y. Lee, N. Nelson-Maney, A. Morris, L. Guo, A. S. Weyrich, M. Sola-Visner, E. Boilard, J. E. Italiano, P. A. Nigrovic

The paper shows that emperipolesis allows neutrophils to transfer membrane to platelets via megakaryocytes, contributing to platelet production and membrane content.

bioRxiv · Dec 21, 2018Cell Biology