Author

P. A. Nigrovic

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Immunology· 5 Cell Biology· 2

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Research Focus:cell type annotation· 6 Organism:human· 6 Research Focus:differential expression· 5 Assay:bulk RNA-seq· 4 Research Focus:cell-cell communication· 4 Approach:experimental assay· 4 Organism:mouse· 4 Approach:statistical model· 4

Frequent Co-Authors

R. Grieshaber-Bouyer· 4 shared D. A. Rao· 3 shared F. A. Radtke· 3 shared A. Morris· 2 shared A. Wactor· 2 shared C. Mueller-Tidow· 2 shared G. Wabnitz· 2 shared H.-M. Lorenz· 2 shared

Activity by Year

2017-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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4 shared papersImmunology

R. Grieshaber-Bouyer

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Author profile →

7 papers

Recent·Most cited

Human and murine neutrophils share core transcriptional programs in both homeostatic and inflamed contexts

N. S. Hackert, F. A. Radtke, T. Exner, H.-M. Lorenz, C. Mueller-Tidow, P. A. Nigrovic, G. Wabnitz, R. Grieshaber-Bouyer

This study compares transcriptional programs of human and murine neutrophils in homeostasis and inflammation, finding shared core programs despite species differences.

bioRxiv · Nov 13, 2022 · PreprintImmunology

Aging and interferon gamma response drive the phenotype of neutrophils in the inflamed joint

R. Grieshaber-Bouyer, T. Exner, N. S. Hackert, F. A. Radtke, S. A. Jelinsky, O. Halyabar, A. Wactor, E. Karimizadeh, J. Schettini, A. H. Jonsson, D. A. Rao, L. A. Henderson, C. Mueller-Tidow, H.-M. Lorenz, G. Wabnitz, , P. A. Nigrovic

This study identifies transcriptional and phenotypic changes in synovial fluid neutrophils from arthritis patients, highlighting IFNγ response and aging as key drivers.

bioRxiv · Nov 16, 2021 · PreprintImmunology

Arthritis Flares Mediated by Tissue Resident Memory T Cells in the Joint

M. H. Chang, A. Levescot, N. Nelson-Maney, R. B. Blaustein, K. D. Winden, A. Morris, A. Wactor, S. Balu, R. Grieshaber-Bouyer, K. Wei, L. A. Henderson, Y. Iwakura, R. A. Clark, D. A. Rao, R. C. Fuhlbrigge, P. A. Nigrovic

This study identifies synovial tissue-resident memory T cells as mediators of arthritis flares in murine models and finds a comparable population in human rheumatoid arthritis tissues.

bioRxiv · Jun 4, 2021Immunology

Neutrophil transit time and localization within the megakaryocyte define morphologically distinct forms of emperipolesis

F. Y. Huang, P. Cunin, F. A. Radtke, R. Grieshaber-Bouyer, P. A. Nigrovic

The paper identifies two distinct forms of emperipolesis based on neutrophil transit time and localization within megakaryocytes.

bioRxiv · Apr 26, 2021Cell Biology

A Systems Immunology Approach Identifies Cytokine-Induced STAT Signaling Pathways Critical to Rheumatoid Arthritis Disease Activity and Treatment Response

S. L. Bridges, J. Ptacek, R. E. Hawtin, D. Sun, B. Louie, E. Evensen, B. Mittleman, A. Cesano, G. Cavet, C. O. Bingham, S. S. Cofield, J. R. Curtis, M. I. Danila, C. Raman, R. Furie, , P. K. Gregersen

bioRxiv · Jul 8, 2019 · PreprintImmunology

Megakaryocyte emperipolesis mediates membrane transfer from intracytoplasmic neutrophils to platelets

P. Cunin, R. Bouslama, K. R. Machlus, M. Martinez-Bonet, P. Y. Lee, N. Nelson-Maney, A. Morris, L. Guo, A. S. Weyrich, M. Sola-Visner, E. Boilard, J. E. Italiano, P. A. Nigrovic

The paper shows that emperipolesis allows neutrophils to transfer membrane to platelets via megakaryocytes, contributing to platelet production and membrane content.

bioRxiv · Dec 21, 2018Cell Biology

Single Cell Transcriptomics And Flow Cytometry Reveal Disease-Associated Fibroblast Subsets In Rheumatoid Arthritis

F. Mizoguchi, K. Slowikowski, J. L. Marshall, K. Wei, D. A. Rao, S. K. Chang, H. N. Nguyen, E. H. Noss, J. D. Turner, B. E. Earp, P. E. Blazar, J. Wright, B. P. Simmons, L. T. Donlin, G. D. Kalliolias, , M. B. Brenner

The paper identifies disease-associated fibroblast subsets in rheumatoid arthritis using single-cell transcriptomics and flow cytometry, revealing subset-specific markers and functional differences.

bioRxiv · May 26, 2017Immunology