Author

K. R. Matthews

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Research Focus:differential expression· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:development & morphogenesis· 1 Research Focus:gene regulatory network inference· 1 Assay:imaging· 1

Frequent Co-Authors

B. Szoor· 2 shared F. Rojas· 2 shared A. Ivens· 1 shared B. Wickstead· 1 shared C. Gadelha· 1 shared D. R. Robinson· 1 shared D. Simon· 1 shared E. M. Briggs· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersMicrobiology

B. Szoor

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

A conserved trypanosomatid differentiation regulator controls substrate attachment and morphological development in Trypanosoma congolense

E. Silvester, B. Szoor, A. Ivens, G. Awuah-Mensah, C. Gadelha, B. Wickstead, K. R. Matthews

This paper identifies TcREG9.1 as a regulator of attachment and morphological development in Trypanosoma congolense, showing its role in surface adhesion and transmission.

bioRxiv · Dec 8, 2023 · PreprintMicrobiology

Extracellular release of two peptidases dominates generation of the trypanosome quorum-sensing signal

M. D. Tettey, F. Rojas, K. R. Matthews

The paper identifies two peptidases, oligopeptidase B and metallocarboxypeptidase I, as dominant in generating the trypanosome quorum-sensing signal through extracellular release.

bioRxiv · Dec 10, 2021Microbiology

Single cell transcriptomic analysis of bloodstream form Trypanosoma brucei reconstructs cell cycle progression and differentiation via quorum sensing

E. M. Briggs, R. McCulloch, K. R. Matthews, T. D. Otto

This study uses scRNA-seq to analyze differentiation in Trypanosoma brucei, identifying gene expression patterns and regulators during cell cycle progression and quorum sensing.

bioRxiv · Dec 11, 2020Microbiology

Positional dynamics and glycosomal recruitment of developmental regulators during trypanosome differentiation

B. Szoor, D. Simon, F. Rojas, J. Young, D. R. Robinson, T. Kruger, M. Engstler, K. R. Matthews

The paper tracks TbPIP39 recruitment to glycosomes during trypanosome differentiation and identifies a regulatory site coordinating signaling and glycosomal development.

bioRxiv · Apr 10, 2019Microbiology