K. Rafie

Giardia intestinalis deoxyadenosine kinase has a unique tetrameric structure that enables high substrate affinity and makes the parasite sensitive to deoxyadenosine analogues

This paper characterizes Giardia intestinalis deoxyadenosine kinase, showing it forms a tetramer with high substrate affinity and sensitivity to deoxyadenosine analogues, making it a potential drug target.

Clinically observed deletions in SARS-CoV-2 Nsp1 affect protein stability and its ability to inhibit translation

The paper investigates how deletions in SARS-CoV-2 Nsp1 affect protein stability and translation inhibition, finding that certain deletions reduce translation inhibition while others impact interferon response.

The structure of enteric human adenovirus 41 - a leading cause of diarrhoea in children

This study determines the structure of enteric HAdV-F41 using cryo-EM, revealing structural differences from non-enteric HAdVs that explain its tissue tropism and pathogenicity.