Long-range coupled motions underlie ligand recognition by a chemokine receptor
K. Rajarathnam, K. M. Sepuru, V. Nair, P. Prakash, A. Gorfe
This study investigates how Site-I interactions in CXCR1 contribute to ligand recognition by CXCL8 through structural plasticity, using NMR and MD simulations.
bioRxiv · Jul 28, 2020Biophysics