Notch3 promotes prostate cancer-induced bone lesion development via MMP3
S. S. Ganguly, G. Hostetter, L. Tang, S. Frank, K. Saboda, R. Mehra, L. Wang, X. Li, E. T. Keller, C. K. Miranti
This study shows Notch3 promotes osteoblastic bone lesions in prostate cancer by inhibiting osteoclasts and enhancing osteoblasts through MMP-3.
bioRxiv · Jul 3, 2019Cancer Biology