K. Shifflett

Serum from COVID-19 patients early in the pandemic shows limited evidence of cross-neutralization against variants of concern

The paper examines serum from early pandemic SARS-CoV-2 patients, finding limited cross-neutralization against variants of concern.

Optimization of single dose VSV-based COVID-19 vaccination in hamsters

This study evaluates two VSV-based COVID-19 vaccines in hamsters, showing intranasal vaccination provides rapid protection against multiple SARS-CoV-2 variants.

Pathogenic and transcriptomic differences of emerging SARS-CoV-2 variants in the Syrian golden hamster model

This study compares the pathogenic and transcriptomic effects of SARS-CoV-2 variants B.1.1.7 and B.1.351 to the ancestral strain in Syrian golden hamsters, finding distinct humoral responses and transcriptional profiles.

A human factor H-binding protein of Bartonella bacilliformis and potential role in serum resistance

This study identifies a factor H-binding protein in Bartonella bacilliformis that contributes to serum resistance by binding host factor H, enhancing bacterial survival in the human host.

Rapid protection from COVID-19 in nonhuman primates vaccinated intramuscularly but not intranasally with a single dose of a recombinant vaccine

A single-dose VSV-based vaccine protected nonhuman primates from COVID-19 within 10 days when administered intramuscularly but not intranasally.

Coxiella burnetii small RNA 12 binds CsrA regulatory protein and transcripts for the CvpD type IV effector, regulates pyrimidine and methionine metabolism, and is necessary for optimal intracellular growth and vacuole formation during infection

This study identifies CbsR12, a small RNA in Coxiella burnetii, which binds CsrA and regulates metabolic genes and a type IV effector, essential for intracellular growth and vacuole formation.