Combined and differential roles of ADD domains of DNMT3A and DNMT3L on DNA methylation landscapes in mouse germ cells
N. Kubo, R. Uehara, S. Uemura, H. Ohishi, K. Shirane, H. Sasaki
This study examines the roles of ADD domains in DNMT3A and DNMT3L in DNA methylation in mouse germ cells, finding that their combined loss leads to severe methylation defects.
bioRxiv · Sep 7, 2023Cell Biology