Pattern Recognition Receptor for Bacterial Lipopolysaccharide in the Cytosol of Human Macrophages
M. Rojas-Lopez, A. S. Zajac, T. E. Wood, K. A. Miller, M. L. Gil Marques, A. C. Hachey, V. Kharbanda, K. T. Egger, M. B. Goldberg
The paper identifies NLRP11 as a cytosolic receptor for bacterial lipopolysaccharide in human macrophages, essential for caspase-4 inflammasome activation.
bioRxiv · Oct 22, 2021 · PreprintMicrobiology