Author

A. C. Hachey

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Approach:microscopy & imaging analysis· 1 Assay:structural biology· 1

Frequent Co-Authors

M. B. Goldberg· 2 shared A. L. Wiscovitch· 1 shared A. S. Zajac· 1 shared B. C. Russo· 1 shared J. K. Duncan· 1 shared K. A. Miller· 1 shared K. T. Egger· 1 shared M. L. Gil Marques· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersMicrobiology

M. B. Goldberg

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Author profile →

2 papers

Recent·Most cited

Pattern Recognition Receptor for Bacterial Lipopolysaccharide in the Cytosol of Human Macrophages

M. Rojas-Lopez, A. S. Zajac, T. E. Wood, K. A. Miller, M. L. Gil Marques, A. C. Hachey, V. Kharbanda, K. T. Egger, M. B. Goldberg

The paper identifies NLRP11 as a cytosolic receptor for bacterial lipopolysaccharide in human macrophages, essential for caspase-4 inflammasome activation.

bioRxiv · Oct 22, 2021 · PreprintMicrobiology

Activation of Shigella flexneri type 3 secretion requires a host-induced conformational change to the translocon pore

B. C. Russo, J. K. Duncan, A. L. Wiscovitch, A. C. Hachey, M. B. Goldberg

This paper shows that host intermediate filaments induce conformational changes in the Shigella T3SS pore, enabling docking and effector secretion.

bioRxiv · Jun 19, 2019Microbiology