PathologybioRxiv
Prolonged podocyte depletion in larval zebrafish resembles mammalian focal and segmental glomerulosclerosis
K. U. I. Hansen, F. Siegerist, S. Daniel…·N. Endlich
This study shows that podocyte-depleted zebrafish larvae develop features resembling human focal and segmental glomerulosclerosis, including proteinuria and PEC activation, and can be used for drug screening.
DOI 10.1096/fj.202000724r