Author

K. U. Saumya

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 4 Biochemistry· 1

Signature Assays, Organisms & Methods

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Organism:virus· 3 Approach:experimental assay· 2 Research Focus:protein folding & dynamics· 2 Assay:protein structure· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Approach:deep learning· 1

Frequent Co-Authors

R. Giri· 5 shared A. Kumar· 3 shared K. Gadhave· 3 shared P. Kumar· 3 shared T. Bhardwaj· 3 shared S. K. Kapuganti· 2 shared M. Vendruscolo· 1 shared N. Garg· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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5 shared papersBiophysics

R. Giri

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5 papers

Recent·Most cited

Met58 and di-acidic motif located at C-terminal region of SARS-CoV-2 ORF6 plays a crucial role in its structural conformations

P. Kumar, K. U. Saumya, T. Bhardwaj, R. Giri

The paper investigates the structural dynamics of the C-terminal region of SARS-CoV-2 ORF6, identifying key residues like Met58 and di-acidic motifs that influence its structural conformations and functional properties.

bioRxiv · Aug 14, 2023Biophysics

The aggregation potential of Zika virus proteome

R. Giri, T. Bhardwaj, K. U. Saumya, K. Gadhave, S. K. Kapuganti, N. Sharma

This study identifies aggregation-prone regions in the Zika virus proteome using computational tools and experimental validation, showing several viral proteins can form amyloid-like fibrils.

bioRxiv · Mar 26, 2022 · PreprintBiophysics

Investigating the conformational dynamics of SARS-CoV-2 NSP6 protein with emphasis on non-transmembrane 91-112 & 231-290 regions

A. Kumar, P. Kumar, K. U. Saumya, R. Giri

This paper investigates the conformational dynamics of SARS-CoV-2 NSP6 protein, focusing on regions 91-112 and 231-290 outside the membrane, using molecular dynamics simulations and reductionist approaches.

bioRxiv · Jul 6, 2021Biophysics

Amyloidogenic proteins in the SARS-CoV and SARS-CoV-2 proteomes

T. Bhardwaj, K. Gadhave, S. K. Kapuganti, P. Kumar, Z. F. Brotzakis, K. U. Saumya, N. Nayak, A. Kumar, N. Garg, M. Vendruscolo, R. Giri

This study investigates protein aggregation in SARS-CoV and SARS-CoV-2 proteomes, finding that several SARS-CoV-2 proteins form cytotoxic aggregates via a nucleation-dependent mechanism.

bioRxiv · May 29, 2021Biophysics

Zika Virus Capsid Anchor Forms Cytotoxic Amyloid-like Fibrils

K. U. Saumya, K. Gadhave, A. Kumar, R. Giri

This study investigates the amyloid-forming propensity of the Zika virus Capsid-anchor (CA) peptide and shows it forms cytotoxic amyloid-like fibrils.

bioRxiv · Nov 13, 2020Biochemistry