N. Garg

Discovery of homogentisic acid as a precursor in trimethoprim metabolism and natural product biosynthesis

The paper identifies homogentisic acid as a precursor in trimethoprim metabolism and natural product biosynthesis using a novel mass spectrometry-based approach.

Bioinspired Dual-Functional Solid Lipid Nanoformulations for Targeted Drug Delivery and Sustained Release for Enhancement of Potency of Albendazole, an Antihelminthic Drug

This paper develops bioinspired solid lipid nanoparticles for targeted drug delivery of albendazole, showing enhanced potency and sustained release against gastrointestinal helminths.

Decoding the Neural Signatures of Valence and Arousal From Portable EEG Headset

This study classifies emotions based on valence and arousal using EEG data from a portable headset, achieving specific RMSE scores on benchmark datasets.

Amyloidogenic proteins in the SARS-CoV and SARS-CoV-2 proteomes

This study investigates protein aggregation in SARS-CoV and SARS-CoV-2 proteomes, finding that several SARS-CoV-2 proteins form cytotoxic aggregates via a nucleation-dependent mechanism.

High-throughput and dosage-controlled intracellular delivery of large cargos by an acoustic-electric micro-vortices platform

The paper introduces a microfluidic platform for high-throughput, dosage-controlled intracellular delivery of large cargos with high viability and efficiency.

Environmental Dependence of the Structure of the C-terminal Domain of the SARS-CoV-2 Envelope Protein

This paper investigates how environmental factors affect the conformation of the C-terminal domain of the SARS-CoV-2 envelope protein, showing it transitions between disordered, membrane-bound, and amyloid states.

Conformational Dynamics of NSP11 Peptide of SARS-CoV-2 Under Membrane Mimetics and Different Solvent Conditions

This study investigates the conformational dynamics of SARS-CoV-2 nsp11 peptide under different membrane mimetics and solvent conditions, revealing its disordered nature and helical propensity in specific environments.

SARS-CoV-2 NSP1 C-terminal region (residues 130-180) is an intrinsically disordered region

This study investigates the conformational dynamics of SARS-CoV-2 NSP1 C-terminal region in isolation and under different solvent environments, finding it intrinsically disordered with conformational changes induced by SDS, TFE, and DOPC.

The Molecular and Microbial Microenvironments in Chronically Diseased Lungs

The paper generates 3D maps of microbiomes and metabolomes in cystic fibrosis lungs, revealing personalized and regiospecific chemical environments and microbial interactions.

Chemical Impacts of the Microbiome Across Scales Reveal Novel Conjugated Bile Acids

The paper identifies novel conjugated bile acids produced by the microbiome in mice and humans using mass spectrometry and a murine 3D model.