Mathematical Modeling Identifies the Role of Adaptive Immunity as a Key Controller of Respiratory Syncytial Virus (RSV) Titer in Cotton Rats
D. Wethington, o. harder, K. Uppulury, W. Stewart, P. Chen, T. King, S. Reynolds, M. E. Peeples, S. Niewiesk, J. Das
The paper uses mathematical modeling to show that adaptive immunity significantly reduces RSV titer in cotton rats, with key kinetic features observed in both in vitro and in vivo experiments.
bioRxiv · Oct 24, 2018Microbiology