Author

W. Stewart

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Immunology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 5 Organism:chicken / avian· 3 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1

Frequent Co-Authors

J. Das· 5 shared D. Wethington· 3 shared G. Giuliani· 2 shared K. Uppulury· 2 shared o. harder· 2 shared P. Chen· 2 shared S. Niewiesk· 2 shared S. Reynolds· 2 shared

Activity by Year

2018-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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5 shared papersMicrobiology

J. Das

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Spatial organization and stochastic fluctuations of immune cells impact clinical responsiveness to immune checkpoint inhibitors in patients with melanoma

G. Giuliani, W. Stewart, Z. Li, C. Jayaprakash, J. Das

The paper develops a spatially resolved model to show how immune cell organization and dynamics influence response to immune checkpoint inhibitors in melanoma patients.

bioRxiv · Dec 6, 2023 · PreprintImmunology

Clonal stochasticity in early NK cell response to mouse cytomegalovirus is generated by mature subsets of varying proliferative ability

D. Wethington, S. Ahmad, M. Potempa, G. Giuliani, O. A. Aguilar, M. Poudel, S. Grassmann, W. Stewart, N. M. Adams, J. C. Sun, L. L. Lanier, J. Das

This study quantifies how clonal stochasticity in NK cell responses to MCMV arises from proliferation and death dynamics of mature NK subsets.

bioRxiv · Sep 7, 2023Immunology

Increased apoptotic priming of glioblastoma enables therapeutic targeting by BH3-mimetics

A. Koessinger, D. Koessinger, K. Kinch, L. Martinez-Escardo, N. Paul, Y. Elmasry, G. Malviya, C. Cloix, K. Campbell, F. Bock, J. O'Prey, K. Stevenson, C. Nixon, M. Jackson, G. Ichim, , S. Tait

This study shows that glioblastoma (GBM) is highly sensitive to BH3-mimetics due to elevated anti-apoptotic BCL-xL and MCL-1 expression, which can be therapeutically targeted.

bioRxiv · Jun 13, 2021 · PreprintCancer Biology

Mutations in bacterial genes induce unanticipated changes in the relationship between bacterial pathogens in experimental otitis media

V. Lakhani, L. Tan, S. Mukherjee, W. Stewart, W. E. Swords, J. Das

The paper investigates how mutations in bacterial genes alter interactions between pathogens in experimental otitis media by analyzing co-infection kinetics in chinchillas.

bioRxiv · Nov 6, 2018Microbiology

Mathematical Modeling Identifies the Role of Adaptive Immunity as a Key Controller of Respiratory Syncytial Virus (RSV) Titer in Cotton Rats

D. Wethington, o. harder, K. Uppulury, W. Stewart, P. Chen, T. King, S. Reynolds, M. E. Peeples, S. Niewiesk, J. Das

The paper uses mathematical modeling to show that adaptive immunity significantly reduces RSV titer in cotton rats, with key kinetic features observed in both in vitro and in vivo experiments.

bioRxiv · Oct 24, 2018Microbiology

Mathematical Modeling Identifies the Role of Adaptive Immunity as a Key Controller of Respiratory Syncytial Virus (RSV) Titer in Cotton Rats

D. Wethington, O. Harder, K. Uppulury, W. Stewart, P. Chen, T. King, S. Reynolds, M. Peeples, S. Niewiesk, J. Das

The paper uses mathematical modeling to show that adaptive immunity significantly reduces RSV titer in cotton rats, with key kinetic features observed in both in vitro and in vivo experiments.

bioRxiv · Oct 24, 2018 · PreprintMicrobiology