cGAMP signaling controls a transient surface-associated lifestyle
Z. F. Hallberg, C. H. Chan, T. A. Wright, P. J. Kranzusch, K. W. Doxzen, J. J. Park, D. Bond, M. C. Hammond
The paper shows that the GacA enzyme in Geobacter sulfurreducens specifically regulates cGAMP levels to control metal reduction genes, despite in vitro promiscuity, through a kinetic model and structural analysis.
bioRxiv · Dec 12, 2018Biochemistry