Paracrine Activin-A Signaling Promotes Melanoma Growth And Metastasis Through Immune Evasion
P. Donovan, O. A. Dubey, S. Kallioinen, K. W. Rogers, K. Muehlethaler, P. Mueller, D. Rimoldi, D. B. Constam
This study shows that paracrine Activin-A signaling in melanoma promotes tumor growth and metastasis by inhibiting anti-tumor immunity and causing muscle wasting.
bioRxiv · Jun 1, 2017Cancer Biology