Cell-intrinsic IL4R alpha independence of large intestinal RELMα+ Ym1+ macrophages
R. Forman, L. B. Logunova, H. Smith, K. Wenyss, I. Mair, L. Boon, J. E. Allen, W. Müller, J. L. Pennock, K. J. Else
This study shows that RELMα+ Ym1+ macrophages in the large intestine can upregulate these markers without IL4R signaling, challenging the idea that IL4/IL13 is required for their activation.
bioRxiv · Dec 17, 2020Immunology