K. Wisser

Chemical potential measurements constrain models of cholesterol-phosphatidylcholine interactions

The paper measures cholesterol chemical potential in lipid membranes and finds it varies significantly with phospholipid composition, suggesting cholesterol availability can be modulated without changing its concentration.

Membrane phase separation drives organization at B cell receptor clusters

The paper proposes a framework for lipid-driven plasma membrane heterogeneity in B cells, supported by observations of receptor phosphorylation in perturbed systems.

Membrane domains and phosphatase exclusion produce robust signaling responses in B cells engaged with natural ligands and artificial cross-linkers presented on lipid bilayers.

This study shows that B cells form robust phase-like domains when engaging with natural ligands or cross-linkers on lipid bilayers, integrating membrane organization and phosphatase exclusion to enhance signaling.