Author

K. X. Liang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:organoid / primary culture· 1

Frequent Co-Authors

A. Chen· 1 shared C. Lundberg· 1 shared C. Tzoulis· 1 shared G. J. Sullivan· 1 shared L. A. Bindoff· 1 shared T. Yangzom· 1 shared Y. Hong· 1 shared

Activity by Year

2023-2023 · peak 1/yr

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7 top collaborators · 21 mutual co-author links

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1 shared paperCell Biology

A. Chen

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1 paper

Recent·Most cited

Hallmark molecular and pathological features of POLG disease are recapitulated in cerebral organoids

K. X. Liang, A. Chen, T. Yangzom, Y. Hong, C. Lundberg, G. J. Sullivan, C. Tzoulis, L. A. Bindoff

This paper develops a cerebral organoid model of POLG disease that recapitulates its molecular and pathological features, including mtDNA depletion and neuronal loss, and shows metformin can alleviate some abnormalities.

bioRxiv · Sep 16, 2023Cell Biology