The luminal AAA+ ATPase torsinA mediates distinct mechanisms of nuclear-cytoplasmic communication by adopting different functional assembly states.
K.-H. Hur, J. W. Hennen, C. A. Saunders, A. Schoenhoefen, P. T. Willey, C. M. Morris, R. H. Ibrahim, R. S. Maisuria, J. D. Mueller, G. W. G. Luxton
This study investigates how torsinA, a luminal AAA+ ATPase, mediates nuclear-cytoplasmic communication by adopting distinct functional assembly states during LINC complex and NPC biogenesis.
bioRxiv · Dec 9, 2021 · PreprintCell Biology