Structural insights into TRAP association with ribosome-Sec61 complex, and translocon inhibition by a CADA derivative
E. Pauwels, N. R. Shewakramani, B. De Wijngaert, A. Camps, B. Provinciael, J. Stroobants, K.-U. Kalies, E. Hartmann, P. Maes, K. Vermeire, K. Das
The paper presents cryo-EM structures of the ribosome-Sec61 complex with TRAP and CK147, showing TRAP's binding and CK147's inhibition mechanism.
bioRxiv · Sep 28, 2022Cell Biology