High-density microbioreactor process designed for automated point-of-care manufacturing of CAR T cells
W.-X. Sin, N. S. Jagannathan, D. B. L. Teo, F. Kairi, D. Sandikin, K.-W. Cheung, Y. H. Lee, R. J. Ram, L. Tucker-Kellogg, M. E. Birnbaum
This paper introduces a high-density microbioreactor for automated CAR T cell manufacturing, achieving clinical dose levels in a small footprint with comparable functional attributes to traditional methods.
bioRxiv · Apr 7, 2023Bioengineering